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CBD Pure CBD Bottle

Joy Organics CBD Bottle

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PureKana offers five flavors of oil, Vanilla, Mint, Natural, Citrus, and Fruity Pebbz, which range from 300 mg to 5,000 mg, depending on the flavor. Our favorite is the Fruity Pebbz, though their Citrus flavor is a close second. With a lineup that’s tried and true, PureKana is a top-tier brand, and one that should be on your shortlist.

If you’re going to call yourself Royal CBD, you’d better come through with a top-tier product. Though Royal currently has only one line of CBD oils, they’ve swiftly become a favorite. They offer full-spectrum CBD extract suspended in premium MCT oil, in 250 mg, 500 mg, 1,000 mg and 2,500 mg dosages. A solid choice if you’re looking for an oil that focuses on craft over taste, Royal CBD will soon have you feeling like a million bucks.

Coming from quality-tested organic sources, CBD Pure’s oil is available in 300 mg, 600 mg and 1,000 mg dosages. While it’s a simple lineup, they have put a lot of investment into delivering a top-tier product, and provide plenty of information on their offerings. I tip my hat to them for being both straightforward and educational.

For a brand that prides itself on its creativity, cbdMD definitely has the formula down pat. They offer oils in 300-7,500 mg dosages. Natural, Berry, Orange and Mint flavors are available for all dosages except the 5,000 mg, which comes in only Natural and Berry. Utilizing a base of MCT oil, this tincture is created from simple ingredients, but packs a serious punch. Although their pricing can get expensive, at up to $339.99 per bottle, cbdMD also offers some of the most powerful dosages on the market. Give them a shot if you’re looking for something extra potent and are doing a deep dive into the effects of CBD.

Cannabis has been used for managing pain and inflammation for thousands of years.

The company has high transparency standards; not only does cbdMD broadly describe their activity from farming to testing, but they also provide batch-specific certificates of analysis for their products, including the results for potency and common contaminants like pesticides, heavy metals, and residual solvents.

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Technical Details

One of the main reasons people are interested in trying CBD oil is because of its pain-killing benefits. We’ll get into the details of how CBD is suggested to help with pain later, along with some suggestions for the best CBD oils for pain and inflammation.

One of the key areas CBD is thought to support osteoarthritis specifically is through the effects on an enzyme known as 5-lipoxygenase — AKA 5-LOX. CBD has been shown to inhibit this enzyme (7), which converts fatty acids into pro-inflammatory compounds. These inflammatory messengers have been shown to be a key component in the underlying inflammation involved with osteoarthritis (8).

If a company is using harsh solvents like butane or propane (or they don’t tell you anything about their extraction methods), it’s a sign that you should look for another brand.

Supercritical CO2 acts just like any other solvent, but with one key benefit — as soon as the pressure is relieved, the gas evaporates completely, leaving behind no harmful chemical residues.

CBD is available in a variety of forms. You can take CBD oil as drops under the tongue or in the form of capsules. If you don't like the taste of CBD oil, CBD gummies might be a better choice for you. CBD topicals, like creams, can also be applied directly to pain points. 

This content is for informational purposes only and does not constitute medical advice; it is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition and before consuming or using any of the products mentioned on this site.

Staci Gulbin, MS, MEd, RD, is a registered dietitian, freelance writer, health editor, and founder of LighttrackNutrition.com. She has been a registered dietitian with the Commission on Dietetic Registration since 2010 and has over a decade of experience in the nutrition and dietetics industry.

CBD for sleep and anxiety

Hemp source is important to note since American-grown hemp has stricter safety and purity standards throughout the planting, harvesting, and manufacturing processes than overseas hemp. Organic and natural farming practices also ensure the hemp is free of pesticides.

Available in multiple strengths, the oil’s 1,000 milligram option is the most popular and delivers 33.33 milligrams of CBD per 1 milliliter serving. The formula also contains over 4 milligrams of secondary cannabinoids, terpenes, flavonoids, and antioxidants to create a more potent blend. R+R Medicinals is a fantastic choice if you’re looking for a completely organic and great-tasting CBD oil.

A 2019 retrospective case study looked at the effects of CBD on sleep and anxiety symptoms. Results showed that nearly 80% of participants who took 25 milligrams of CBD oil daily for one month in capsule form saw reduced anxiety scores and improved sleep.

It is third-party lab tested for quality, contains organic MCT coconut oil, and is free of artificial flavors and preservatives.