Posted on

is cbd oil a blood thinner

Currently, sparse research suggests that CBD can illicit problematic interactions with certain other prescription drugs. The findings are far from conclusive — further research is still needed on CBD’s interaction with different medications. Many doctors and researchers urge individuals using CBD medically or recreationally to be cautious about mixing it with other prescriptions and to consult healthcare providers about possible interactions.

Patients using Plavix or clopidogrel should consult their physicians as to whether they should use CBD.

Image lightbox

Patients taking metoprolol or other beta-blockers should consult their doctor as to whether to consume CBD.

Eliquis (generically called apixaban) is a blood thinner used to lower the risk of stroke or a blood clot in veins, the heart, the lungs, and the legs following knee or hip replacement surgery. Eliquis increases the risk of severe bleeding, and patients taking Eliquis are typically prescribed precise dosages by their doctor.

Statins are a classification of drugs designed to lower cholesterol and protect against heart attack and stroke. Common side effects of statins are muscle soreness, blood sugar increase, headaches, and nausea.

Absolutely. Inhaled CBD gets into the blood the fastest, reaching high concentration within 30 minutes and increasing the risk of acute side effects. Edibles require longer time to absorb and are less likely to produce a high concentration peak, although they may eventually reach high enough levels to cause an issue or interact with other medications. Topical formulations, such as creams and lotions, may not absorb and get into the blood in sufficient amount to interact with other medications, although there is very little information on how much of CBD gets into the blood eventually. All of this is further complicated by the fact that none of these products are regulated or checked for purity, concentration, or safety.

Many drugs are broken down by enzymes in the liver, and CBD may compete for or interfere with these enzymes, leading to too much or not enough of the drug in the body, called altered concentration. The altered concentration, in turn, may lead to the medication not working, or an increased risk of side effects. Such drug interactions are usually hard to predict but can cause unpleasant and sometimes serious problems.

CBD has the potential to interact with many other products, including over-the-counter medications, herbal products, and prescription medications. Some medications should never be taken with CBD; the use of other medications may need to be modified or reduced to prevent serious issues. The consequences of drug interactions also depend on many other factors, including the dose of CBD, the dose of another medication, and a person’s underlying health condition. Older adults are more susceptible to drug interactions because they often take multiple medications, and because of age-related physiological changes that affect how our bodies process medications.

Does the form of CBD matter?

The researchers further warned that while the list may be used as a starting point to identify potential drug interactions with marijuana or CBD oil, plant-derived cannabinoid products may deliver highly variable cannabinoid concentrations (unlike the FDA-regulated prescription cannabinoid medications previously mentioned), and may contain many other compounds that can increase the risk of unintended drug interactions.

Researchers from Penn State College of Medicine evaluated existing information on five prescription CBD and delta-9-tetrahydrocannabinol (THC) cannabinoid medications: antinausea medications used during cancer treatment (Marinol, Syndros, Cesamet); a medication used primarily for muscle spasms in multiple sclerosis (Sativex, which is not currently available in the US, but available in other countries); and an antiseizure medication (Epidiolex). Overall, the researchers identified 139 medications that may be affected by cannabinoids. This list was further narrowed to 57 medications, for which altered concentration can be dangerous. The list contains a variety of drugs from heart medications to antibiotics, although not all the drugs on the list may be affected by CBD-only products (some are only affected by THC). Potentially serious drug interactions with CBD included

While generally considered safe, CBD may cause drowsiness, lightheadedness, nausea, diarrhea, dry mouth, and, in rare instances, damage to the liver. Taking CBD with other medications that have similar side effects may increase the risk of unwanted symptoms or toxicity. In other words, taking CBD at the same time with OTC or prescription medications and substances that cause sleepiness, such as opioids, benzodiazepines (such as Xanax or Ativan), antipsychotics, antidepressants, antihistamines (such as Benadryl), or alcohol may lead to increased sleepiness, fatigue, and possibly accidental falls and accidents when driving. Increased sedation and tiredness may also happen when using certain herbal supplements, such as kava, melatonin, and St. John’s wort. Taking CBD with stimulants (such as Adderall) may lead to decreased appetite, while taking it with the diabetes drug metformin or certain heartburn drugs (such as Prilosec) may increase the risk of diarrhea.

Products containing cannabidiol (CBD) seem to be all the rage these days, promising relief from a wide range of maladies, from insomnia and hot flashes to chronic pain and seizures. Some of these claims have merit to them, while some of them are just hype. But it won’t hurt to try, right? Well, not so fast. CBD is a biologically active compound, and as such, it may also have unintended consequences. These include known side effects of CBD, but also unintended interactions with supplements, herbal products, and over-the-counter (OTC) and prescription medications.

Several factors, such as your general tolerance, weight, and health can influence your likelihood to experience some side effects or interactions. Given the many variables that need to be considered, it’s strongly recommended to speak to your doctor before taking CBD oil, especially if you’re taking blood thinning medication. Your healthcare practitioner will need to take into account the processing time of CBD oil and make adjustments to your medication so they can safely add it to your medication regimen, with minimal system disruption. In doing so, you may be asked to start with a lower-than-recommended CBD oil dose (to help build a CBD oil tolerance) and gradually increase over time if required.

Our bodies have a system called the Cytochrome P-450 System which metabolizes toxins in the body. Antibiotics have an effect on this system, and CBD has also been found to inhibit this system. This can have a negative effect because when CBD inhibits the system, it alters the way the system metabolizes other drugs — such as antibiotics. In rare cases, this can lead to overdosing on the antibiotic because your body is not processing the drug properly.

Effects of CBD oil on blood thinners

There can be adverse effects of taking both CBD and antibiotics regularly, so it’s something you should absolutely ask your medical professional before doing so, just as you would with any other medication you may be taking. They will know what is safe for you based on what medications you’re consuming.

Another study on the anticoagulant effects of cannabis has shown that the cannabinoids cannabinol and THC in full-spectrum or broad CBD oil can prevent the formation of blood clots or thrombosis by extending the time it takes for blood clots to form (two times longer to form clots compared to subjects that don’t use CBD).

If you live in a state where cannabis has been decriminalized or legalized, you may have noticed that tons of CBD products are being sold all around you. Cannabidiol (CBD oil) is legal in states with medical marijuana and is extracted from the flowers or buds of marijuana and hemp plants. CBD is not the same thing as the chemical of marijuana THC — THC produces the high many people get from marijuana, whereas CBD is cited for helping with pain, relaxing, sleep, and even skincare. Amazingly, CBD is also being used to prevent seizures and treat epilepsy. The U.S Food and Drug Administration approved CBD medication to treat two rare forms of childhood epilepsy.