A 2013 review concluded that CBD was a potential candidate for an inflammatory bowel disease medication. However, a 2017 clinical trial found CBD to be safe, but ineffective for the condition. The authors said their results could “be due to the small dose of CBD, the small number of patients in the study, or the lack of the necessary synergism with other cannabinoids.”
Inflammation plays an important role in a number of diseases, including asthma, allergies, inflammatory bowel disease, celiac disease, and a number of autoimmune conditions, as well as in other seemingly unrelated conditions, such as cancer, heart disease, and diabetes. Could CBD’s anti-inflammatory effects be used in any of these applications?
Inflammation, or the inflammatory response, is an aspect of the body’s immune response. While short-term inflammation can be protective, chronic inflammation is linked to several diseases, including heart disease, cancer, diabetes, rheumatoid arthritis, inflammatory bowel disease, and Alzheimer’s.
Human health: What do studies say?
Cannabinoids, including CBD, are believed to be anti-inflammatory. Several studies in cells, rodents, and humans support the idea that CBD may be an effective anti-inflammatory, but more research is needed to determine how it works and the best applications for specific types of inflammation.
Such medications have risks and side effects, however. Some people choose to take a more preventative approach to treating inflammation, such as consuming an anti-inflammatory diet, and taking anti-inflammatory supplements. Could CBD contribute to a more natural approach to treating inflammation?
Inflammation often goes hand in hand with pain. The most common symptoms of inflammation include pain, heat, redness, and swelling. Typically, inflammation is treated with anti-inflammatory medications, including both non-steroidal anti-inflammatory drugs (NSAIDs) and steroid medications.
CBD is known to be an anti-inflammatory and it is likely one of the safest medicines to provide such an effect.
She notes that she has seen patients successfully transition from anti-inflammatories and steroids to medical cannabis, but that this should only be done under the supervision of a doctor or pharmacist.
CBD shows potential as a plant-derived anti-inflammatory without the side effects of medications. Photo by: Gina Coleman/Weedmaps
Adam Kemp is a professional basketball player who turned to CBD products after breaking a bone in his back at the beginning of the 2017 season.
Research on CBD in animal models abounds and the cannabinoid seems to be able to interact with the immune system, reduce inflammation, and reduce pain from a number of conditions. Studies date back as far as 2009 but the most recent are highlighted here.
“I have had IBD for over 20 years, and had been on a range of medications, from steroids to opioids,” Orr told Weedmaps. “The steroids helped a lot with inflammation but not with the pain, and the Oxy was like trying to crack a nut with a sledgehammer — brutal side effects. It made me feel awful due to bad nausea and extreme fogginess.”
Inflammation occurs as a natural protective response when the body is harmed. There are two types of inflammation: acute and chronic.
Acute inflammation occurs following an injury, infection, or illness. The immune system unleashes immune cells to the affected area to protect it, causing redness and swelling.
According to the Centers for Disease Control and Prevention (CDC) , every 6 in 10 adults in the United States alone has a chronic disease, and 4 in 10 of them have two or more chronic pain issues. CDC also mentions that chronic pain and inflammation diseases lead the nation’s $3.5 trillion annual health care costs.
It is also best to apply CBD 1-2 times per day every 6-8 hours as the CBD bioavailability for topical applications lasts 6-8 hours. If you want to learn more about CBD dosing, we recommend watching the video below as it covers every essential component of CBD dosing.
#4 – Lazarus Naturals
People suffering from pain that’s directly caused by inflammation may be the first to celebrate if CBD is ever fully embraced as a mainstream anti-inflammatory medication. If it’s true that CBD reduces inflammation, however, this non-intoxicating, non-toxic cannabinoid may one day be hailed as a genuine panacea .
Sublingual administration refers to the act of placing a substance under your tongue. CBD tinctures, also known as CBD oils, are designed to be placed under your tongue for at least 30 seconds before swallowing.
Consuming CBD through oral administration does have lower peak plasma levels . Still, the effects last for a more extended time than smoking CBD-rich hemp and sublingually with CBD oil tinctures.