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how does cbd work in the brain

In reality, psychoactive chemicals act on the central nervous system (CNS) and alter brain function. As a result, they cause temporary changes in consciousness, behavior, mood, or perception. CBD impacts mood and other behaviors, so there are psychoactive effects. In this guide, we illustrate five of them.

Now that we have explored a little of the science behind CBD’s effects; let’s look at five specific ways it impacts the human brain.

How Does CBD Affect Your Brain?

While scientists are not completely sure, they believe that CBD also affects the way in which these receptors respond to the pain signals we receive, which helps reduce pain and inflammation.

The cannabinoid’s effects on the brain appear to be many and profound, but we need more confirmatory studies. We advise all readers to steer clear of CBD sellers that try to portray cannabidiol as a ‘cure-all.’ There is no question that the existing research is exciting, but it would be irresponsible to draw too many conclusions just yet.

The brain has protein receptors throughout it that respond to endocannabinoids.

[8] Shannon S, Lewis N, Lee H, Hughes S. Cannabidiol in Anxiety and Sleep: A Large Case Series. Perm J. 2019;23:18–041.

[4] Bielawiec P, Harasim-Symbor E, Chabowski A. Phytocannabinoids: Useful Drugs for the Treatment of Obesity? Special Focus on Cannabidiol. Front Endocrinol. 2020;11:114.

Evidence-based tools to empower you to live a healthier, longer life.

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[1] Wheeler M, Merten JW, Gordon BT, Hamadi H. CBD (Cannabidiol) Product Attitudes, Knowledge, and Use Among Young Adults. Subst Use Misuse. 2020 Feb 24;1–8.

Δ9-THC is known for producing psychoactive effects in the body through the activation of two receptors in the central nervous system called CB1 and CB2.[2,3] The activation of these receptors triggers physiological processes across multiple organ systems, most notably the release of neurotransmitters from the central nervous system that impart the psychoactive effects associated with feeling “high”.[4]

[7] Larsen C, Shahinas J. Dosage, Efficacy and Safety of Cannabidiol Administration in Adults: A Systematic Review of Human Trials. J Clin Med Res. 2020 Mar;12(3):129–41.

In fall, a pair of high-profile Stanford researchers launched a medical company to develop CBD-based therapies for conditions such as arthritis, Crohn’s disease, and multiple sclerosis.

Epidiolex contains very high levels of CBD — far higher than the amounts found in treats and drinks being sold today. For example, the average dose for an 8-year-old child taking Epidiolex is roughly 650 milligrams of CBD per day. By comparison, most CBD cookies, coffees, and creams contain about 5 to 20 milligrams of CBD.

Epidiolex’s approval is bad news for the CBD treat industry, however. It is because CBD is now a federally-approved prescription drug, according to Sharpless, that food and beverage vendors can’t legally add CBD to anything edible.

New drug companies have been sprouting up with the goal of capitalizing on CBD's potential therapeutic effects.

In June 2018, a prescription CBD-based epilepsy drug called Epidiolex became the first of its kind to be approved by the federal government.

These days, you’ll find CBD being sold in everything from cupcakes to lattes. Sellers claim the compound has a variety of benefits, including anxiety relief and help with sleep and pain. But so far, there’s little solid evidence to back up those claims.

Called Katexco Pharmaceuticals, the company is exploring whether CBD might help treat digestive conditions characterized by swelling and inflammation, such as Crohn’s and irritable bowel disease. Katexco is based in Canada but has a US subsidiary in Silicon Valley.

But starting in February, health-department officials in New York City began to crack down on some CBD vendors, warning of bans and fines.