CBD is a cannabinoid that may relieve pain, lower inflammation and decrease anxiety without the psychoactive ‘high’ effect of THC.
A Cochrane review in 2015 looked at all the research available looking into cannabis based medicine as a treatment for nausea and sickness in people having chemotherapy for cancer. It reported that many of the studies were too small or not well run to be able to say how well these medicines work. They say that they may be useful if all other medicines are not working.
CBD oil, cannabis oil and hemp oil
The plant produces a resin that contains a number of substances or chemicals. These are called cannabinoids. Cannabinoids can have medicinal effects on the body.
The main cannabinoids are:
Scientists also discovered that cannabinoids can:
There is much about CBD that is still unknown. It has largely gone unstudied because, until 2018, it was considered a schedule I drug by the U.S. Drug Enforcement Administration (DEA). A schedule I drug is a drug that has been declared illegal by the DEA because of safety concerns over its potential for abuse and because there is no accepted medical use for it. Then, in September 2018, the DEA updated CBD’s status to become a schedule V drug. Schedule V drugs have a lower potential for abuse and are deemed to have some medical use.
Studies to answer this question are underway. Some scientists are studying whether CBD could relieve some of the side effects of cancer and its treatment, such as pain, insomnia, anxiety, or nausea. Other scientists are studying whether CBD could potentially slow or stop the growth of cancer.
What is CBD?
There is currently 1 CBD treatment approved by the U.S. Food and Drug Administration (FDA) called Epidiolex, which is used to treat a rare and severe form of epilepsy in children. There are not currently any FDA-approved CBD medications for treating cancer or side effects of cancer treatments.
It is also important to note that some studies have shown that CBD might interfere with how your body processes cancer drugs, called a drug interaction. This might make cancer treatments more toxic or make them less effective. More research is needed on these effects, too. For these reasons, always tell your oncologist if you’re thinking about using CBD before you take it.
There have been some studies that show that CBD, alone or together with THC, may relieve pain, insomnia, or anxiety, but these studies were not specific to people with cancer. While no studies to date have shown that CBD eases these side effects specifically in people with cancer or people receiving cancer treatment, some people with cancer have reported benefits in taking CBD, such as helping with nausea, vomiting, depression, and other side effects. According to ASCO guidelines, your doctor may consider prescribing cannabinoids for chronic pain management if you live in a state where it is legal. However, ASCO guidelines state that there is not enough evidence to support the use of cannabinoids for preventing nausea and vomiting in people with cancer receiving radiation therapy or chemotherapy.
According to the Controlled Substances Act, all derivatives of cannabis with zero to less than 0.3 percent THC (delta-9-tetrahydrocannabinol) are considered legal. Cannabis plants may vary in THC and CBD content. So depending on the plant source, cannabis oils which have zero to less than 0.3 percent are acceptable.
And since cancer is due to the abnormal proliferation and mutation of cells, the medicinal cannabinoids in cannabis oil is known to help kill abnormal cancer cells especially in the early stages of cancer.
When getting the higher end of the spectrum from extraction, this highly-potent cannabis oil can interact with the body?s endocannabinoid system. The endocannabinoid system has everything to do with the regulation of different body functions including mood, behavior, appetite, pain, sleep, energy, and more. In addition, the endocannabinoid system is also responsible for cell growth and apoptosis.
Once they bind together, the receptor activation can then help the endocannabinoid system in signaling an antitumorigenic warning. Which means, it impairs cancer development through inhibiting reproduction, metastasis, and tumor angiogenesis.
As these cells grow and divide, they become more uncontrollable. And since they no longer respond to apoptosis, they tend to expedite cell proliferation and ignore the other signals from ?normal cells.? That is why the endocannabinoid system is an extremely important system in the body because it also helps in modulating cell growth and death.