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dr chris shade cbd oil

Gazella: Right. It sure seems like CBD oil, hemp oil, is a valuable tool that clinicians can use in their clinical practice.

Gazella: What about when we began, we talked about the availability. Do you see things loosening up a little bit?

Now, a lot of what CBD does, it does through interacting with receptors, and gene triggers, like nuclear transcription factors, like NRF-2, which turns up all your glutathione genes. Now, the receptors and those transcription factors react to peak doses. Level versus time, here’s a regular CBD oil. Here’s ours. You get a very high transient peak dose. You saturate the system. You’re able to work very well on the brain. You’re able to hit all of those transcription factors. You’re able to interact with all of those membranes, and everything happens very quickly, and you get a very strong effect.


Christopher W. Shade, PhD, founder and CEO of Quicksilver Scientific, specializes in the biological, environmental, and analytical chemistry of mercury in all its forms and their interactions with sulfur compounds, particularly glutathione and its enzyme system. He has patented analytical systems for mercury speciation (separation of different forms of mercury), founded the only clinical lab in the world offering mercury speciation in human samples, and has designed cutting edge systems of nutraceuticals for detoxification and antioxidant protection, including advanced phospholipid delivery systems for both water- and fat-soluble compounds. Quicksilver Scientific is recognized globally for innovating on behalf of the pharmaceutical and nutraceutical industries. Shade earned his PhD from the University of Illinois Urbana-Champaign and his undergraduate degree in Environmental Chemistry is from Lehigh University. Shade is regularly sought out to speak as an educator on the topics of mercury, environmental toxicities, neuroinflammation, immune dysregulation, and the human detoxification system for practitioners and patients in the United States and internationally.

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Shade: They just happen to be antidepressants to your body that get metabolized down different pathways according to their chemical nature. Your breakdown doesn’t care whether it’s an antidepressant or whether it’s testosterone. It’s got a chemical nature, and it’s got to fit into the cytochrone that breaks it down. You get a list of antidepressants, they have different chemical natures, and they go into different cytochrome P450 enzymes to break down, and CBD interacts with two or three of those enzymes. If the antidepressant interacts with the same enzyme CBD does, then there could be an interaction, and if it doesn’t, then there’s no interaction. It’s not about antidepressants.

Gazella: It’s interesting. I would like to stay on dosing. Is it complicated to dose from a practitioner’s standpoint? Because you do have such a diverse offering of conditions that it can help. Is the dosing-

Born in a toxic steel town, Dr. Shade created Quicksilver Scientific to combat the environmental toxicity he personally experienced. Inspired by philosophy, guided by science, and driven to create, he patented a mercury speciation diagnostic process to analyze human toxicity. In addition, he created Quicksilver Delivery Systems® nanoparticle technology to increase the bioavailability of supplements and protocols leading to higher efficacy products without the prick of a needle.

His current focus is at the intersection of neuro-inflammatory issues, immune dysregulation, toxicity, and infection – specifically how to peel away the layers of overlapping dysfunction in the sick individual until you get to a point at which the system rights itself.

In this episode, Dr. Michael Karlfeldt and Dr. Chris Shade Ph.D. discuss the endocannabinoid system and the effect of CBD on chronic conditions such as Anxiety, ADHD, Autism, Auto-immune conditions such as rheumatoid arthritis, type 1 Diabetes, Hashimoto’s, and even cancer.


Endocannabinoids, also called endogenous cannabinoids, are molecules made by your body. They’re similar to cannabinoids, but they’re produced by your body.

These help keep internal functions running smoothly. Your body produces them as needed, making it difficult to know what typical levels are for each.

There are two main endocannabinoid receptors:

CBD provides what Dr. Shade refers to as “Neuro-endo-immune poise, or balance”. Neuro means neurotransmitters. Endo is endocrine or hormone, and immune is obvious. It’s the immune system. Neurologically is how we used it the most, for damping neuro-inflammation. Focusing on the root cause of the problem and supporting the body in detoxification.

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