Studies on CBD also have raised concerns about possible interactions with other drugs.
“About 2 to 3 percent of individuals taking CBD actually had to discontinue because their liver enzymes went so high it was of concern to the people running the study,” he said.
Because of the legally murky nature of marijuana, the FDA has not stepped in to regulate products like CBD oil, Bonn-Miller said. States are struggling to put regulations in place, but they don’t have the deep pockets of the federal government.
Potential Interactions With Other Meds
This could mean that people taking anti-epilepsy drugs alongside CBD will need to adjust their dosage downward to avoid side effects, Welty noted.
There also are concerns about both the quality of CBD oil being produced and its potential side effects, the experts added.
“That’s a problem because THC can increase anxiety. It can actually make seizures worse. Those are the sorts of things you need to be careful about,” Bonn-Miller said.
CBD that is extracted from other cannabis plants is still illegal on the federal level, but may be legal under state law.
While Blessing and Haney both say that CBD shows a lot of promise, they agree that the CBD products on the market (excluding the seizure drug Epidiolex) are suspect.
Y ou might have seen it in your neighborhood health store, your local spa or your corner coffee shop. CBD, aka cannabidiol, is getting mixed into cocktails, lotions and drinks.
Why do people use CBD products?
Patients who take CBD without knowing what they are getting are “just throwing their money away,” Haney says.
“Take the time to get the best information you can. It’s a complex subject. The details really matter,” said Blessing.
“I’m a believer, obviously. I can say, absolutely, for myself this works,” Richards says. “I have arthritis in my knee. If I don’t take CBD, I’m going to feel it come back in a day or two.”
Available CBD products meant to be taken orally (besides Epidiolex) generally have poor “bioavailability,” says Blessing, “so only a small fraction of CBD you swallow makes it into your bloodstream.”