Epidiolex was the first prescription drug  approved by the Food and Drug Administration (FDA) with cannabidiol. Although the drug is used to treat seizures, it may help us understand a maximum tolerable dose range. For people taking Epidiolex, the recommended range is between 2.5 milligrams per kilogram (mg/kg) twice a day up to a maximum of 10 mg/kg twice a day.
The company touts a 7-step process to produce some of the highest quality CBD products available. Their process includes supercritical CO2 extraction and THC removal at the cGMP-compliant facilities. Additionally, all their items undergo independent third-party testing which appears as a QR code on their labels for customer transparency.
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Frequently Asked Questions
Royal CBD is a growing company based out of California. Their emphasis is on transparency and claims that customers “can read us like a book” as they keep their website and product design simple and straightforward.
Joy Organics was founded by the Smith family and continues to be a family run business. Their journey started from seeking natural alternatives to support their health and wellness and it ended up turning into a passion and business opportunity.
Studies have suggested that CBD can be an effective supplement for helping with nerve pain. It’s thought that CBD works by stopping or slowing pain signals from your nerves to your brain.
About 1 in 10 people in the United States  live with neuropathy or nerve pain. According to Mayo Clinic  , symptoms can range from numbness, tingling, and pain, to even more serious conditions like muscle weakness or difficulty moving.
If you compare this to the fact that for every thousand users of anti-inflammatory drugs, three will have heart attacks and one of those will be fatal you can see that the option of trying CBD oil for pain becomes very attractive.
CBD is a compound from the cannabis plant called Cannabidiol.
What Is CBD Oil?
I tend to advise people to start with a middle strength product though there is nothing wrong with starting low and working upwards either. However, my reasoning is that if you start too low and nothing happens the temptation is to think that CBD does not work for you when it may only have needed a stronger product to make a difference.
Getting high and getting stoned are two different effects from different strains of the cannabis plant which have varying proportions of cannabinoids in them. The cannabinoid that gets you high/stoned is tetrahydrocannabinol (THC).
We find our oils are more calming for most people whilst our Absorb range is more energising.
CBD stands for cannabidiol, a non-intoxicating substance found in cannabis. Photo by: Gina Coleman/Weedmaps
A 2012 literature review published in the Journal of Experimental Medicine examined at least one way that cannabinoids suppress inflammatory and neuropathic pain, by targeting alpha-3 glycine receptors. Citing the difficulty of treating neuropathic pain, the researchers also noted that CBD might be able to address the persistent discomfort associated with a range of diseases.
In a 2018 article for Harvard Health Publishing, Dr. Peter Grinspoon, a Boston-based primary care physician and Harvard Medical School professor, discussed prior research on CBD for pain relief in conditions related to inflammation.
CBD may also relieve neuropathic pain by activating the brain’s serotonin receptors. Neuropathic pain disrupts normal serotonin function, and a 2019 study in the journal Pain demonstrated the ability of CBD to relieve neuropathic pain in animals, due to CBD’s ability to restore serotonin function. Authors of a similar study published in Brain Research concluded that the interaction of CBD with serotonin receptors could potentially be helpful for people with diabetic neuropathy.
Many medical experts are tentatively on board with cannabis as a viable treatment option for chronic pain and many see potential in CBD. Photo by: Gina Coleman/Weedmaps