The uric acid forms naturally from the breakdown of purines. When you consume too many purine-rich products, your body will produce more uric acid than it can excrete, and its concentrations will become too high.
The best approach to dosing CBD for gout is to start low (say 5–10 mg daily) and gradually increase the dosage until you reach the amount that provides the desired relief. If you don’t notice any changes in your symptoms after a week, you may add another 5-10 mg to your dosage and test it out for another week. Once you’ve found an effective dose, you can stick to it, as people don’t build a tolerance to CBD.
Does CBD Help with Gout?
90% of gout cases occur when the kidney cannot get rid of uric acid properly.
The ECS regulates mood, memory, emotional processing, cognition, sleep, body temperature, fertility, immune response, pain, and more.
“At a time when we are trying to reduce the use of pain relievers, CBD oil can be an effective approach to managing the pain of arthritis. Researchers have also recognized the role that CBD could play in reducing the pain-causing inflammation of arthritis.”
One of the benefits of CBD is that its side effects are extremely rare, and minor, including diarrhea, nausea, and tiredness. Other medications used to treat gout can have much more serious side effects. Cannabis also has no risk of worsening your gout if it doesn’t work.
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When uric acid crystals accumulate in a joint, the body’s immune system is triggered by cytokines that flood the area with white blood cells, causing inflammation. CBD has been shown to control inflammation  by its effects on the immune system.. It also suppressed IL-6 cells, thus decreasing tissue injuries.
The Chinese and other civilizations used cannabis as early as 2900 BCE to treat joint pain and gout. But modern research is in its infancy with regard to using CBD oil for gout. However, some studies have indicated that cannabis may be beneficial in treating the joint pain and inflammation linked to the disease without the unpleasant side effects of some prescription medications.
Another 2018 study published in the Journal of Headache Pain reported positive findings from a cohort of medical cannabis patients. Researchers found that cannabis varieties high in the terpenes of caryophyllene and myrcene (the most prevalent chemovars on the market at the time of the study) were most successful in treating headaches, migraines, and other pain disorders, including arthritis. Again, such findings could be hopeful news for arthritis patients who are being treated specifically to relieve pain related to gout.
Holistic healthcare practitioner Debra Rose Wilson, Ph.D., has also acknowledged the potential benefits of treating painful inflammatory conditions, including gout, with CBD. In 2018, Wilson wrote in Medical News Today: “At a time when we are trying to reduce the use of pain relievers, CBD oil can be an effective approach to managing the pain of arthritis. Researchers have also recognized the role that CBD could play in reducing the pain-causing inflammation of arthritis.”
Actor Sir Patrick Stewart noted to the Huffington Post that he’s found relief from osteoarthritis with the use of cannabis topicals. Photo by: Gina Coleman/Weedmaps
In an interview with Canadian Broadcasting Corp. (CBC) Radio, McDougall analyzed the nerve endings of arthritis sufferers, saying: “They’re all bare, they’re all raw and responsible for feeling a lot of pain. What we hypothesize is that by locally administering these cannabis-like molecules to those nerves, we’d actually be able to repair them and reduce the pain of arthritis.”