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cbd oil for bpd

Borderline Personality Disorder (BPD) is a chronic debilitating psychiatric disorder characterized mainly by emotional instability, chaotic interpersonal relationships, cognitive disturbance (e.g., dissociation and suicidal thoughts) and maladaptive behaviors. BPD has a high rate of comorbidity with other mental disorders and a high burden on society. In this review, we focused on two compromised brain regions in BPD – the hypothalamus and the corticolimbic system, emphasizing the involvement and potential contribution of the endocannabinoid system (ECS) to improvement in symptoms and coping. The hypothalamus-regulated endocrine axes (hypothalamic pituitary – gonadal, thyroid & adrenal) have been found to be dysregulated in BPD. There is also substantial evidence for limbic system structural and functional changes in BPD, especially in the amygdala and hippocampus, including cortical regions within the corticolimbic system. Extensive expression of CB1 and CB2 receptors of the ECS has been found in limbic regions and the hypothalamus. This opens new windows of opportunity for treatment with cannabinoids such as cannabidiol (CBD) as no other pharmacological treatment has shown long-lasting improvement in the BPD population to date. This review aims to show the potential role of the ECS in BPD patients through their most affected brain regions, the hypothalamus and the corticolimbic system. The literature reviewed does not allow for general indications of treatment with CBD in BPD. However, there is enough knowledge to indicate a treatment ratio of a high level of CBD to a low level of THC. A randomized controlled trial investigating the efficacy of cannabinoid based treatments in BPD is warranted.

Keywords: Borderline personality disorder; cannabidiol; corticolimbic system; endocannabinoid system; hypothalamus; pharmacological treatment.

Endocannabinoids are sent throughout the body by the ECS to achieve and maintain the body’s internal homeostasis, or balance, among all of is working parts. In many psychiatric disorders, symptomatic or episodic behaviours can be traced back to overactive neurons, which send too many neurotransmitters from presynapse to postsynapse and overload receptors.

This is where CBD comes into the picture. When you ingest CBD, you ingest certain plant-derived cannabinoids, which act like the endocannabinoids the body produces naturally. The endocannabinoid system (ECS) produces endocannabinoids to regulate the body’s internal functions and control how we think, feel and react to things happening in the world around us.

There is no single, miracle fix for BPD. Managing BPD is incredibly difficult and requires hours of therapy and hard work. With the right treatment combination, though, people with BPD can still lead wonderful and fulfilling lives. This article is not to suggest that CBD can replace existing BPD treatment, or to guarantee that CBD will even work for everyone with BPD who tries it.

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Because BPD is a personality disorder, treatment options are limited. Behavioural therapies like cognitive behavioural therapy (CBT) and dialectical behavioural therapy (DBT) are the most effective treatment options for BPD. There are no medications designed specifically for BPD, but antidepressant, anti-anxiety and antipsychotic medications are often prescribed to BPD patients to address certain symptoms like depression, anxiety, dissociation, paranoia and intense anger. The benefit of these medications for people with BPD, however, remain unclear, and talk-therapy is often the first line of treatment for BPD.

Approximately 1.6 percent of adults in the U.S. suffer from borderline personality disorder (BPD), a condition characterized by difficulty regulating emotions, impulsivity, low self-image and problems creating and maintaining personal relationships.

Endocannabinoids do not follow what is considered the typical path of a chemical synaptic signalling, which is for a neurotransmitter to flow from a presynaptic neuron to a postsynaptic neuron and bind to a specific receptor. Instead, endocannabinoids flow backward from postsynaptic neurons to presynaptic neurons in a process called retrograde inhibition.

CBD products made from or with hemp oil can also be beneficial to people struggling with BPD. Hemp oil is high in Omega-3 fatty acids, which could have an anti-inflammatory effect on the brain and help cognitive function. And many psychiatric disorders, including BPD, correlate with a deficiency in Omega-3 fatty acids in the body. Research on Omega-3 fatty acid supplementation found it to be an effective treatment method for both children and adults with BPD.

CBD oil can help make changes in brain chemistry that may help people with BPD gain control over their feelings.

People who suffer from depression and anxiety seem to manifest reduced levels of serotonin. Similarly, people with BPD exhibit lowered serotonin levels.

Why People Are Turning to CBD for BPD

The therapeutic effects of cannabinoids, such as CBD, are realized by their interaction with the body’s endocannabinoid system (ECS) and its specialized cannabinoid receptors.

Still, CBD looks promising for BPD patients as a possible treatment for symptoms such as anxiety, depression, and inflammation.

With better regulation of serotonin, CBD could help stabilize mood, which, in turn, combats the adverse effects of anxiety and depression that come along with BPD.