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cbd long term side effects

CAUTION: Fatty foods may increase how CBD is absorbed by the body.

By acting on the ECS, CBD may have many different effects on the body. Examples include: balancing the body’s overall physical functions (homeostasis), reducing pain sensation, and lessening the body’s reaction to injury or infection (inflammation).

CAUTION: Taking CBD with other herbs that cause drowsiness or sleepiness may increase this effect.

CBD and Medical Conditions

Many studies of CBD, including its side effects, are in their early stages. Most people tolerate CBD well.

CBD is an herbal remedy–a treatment that comes from a plant — in this case it is the cannabis sativa plant. Cannabis sativa has been used for thousands of years for its healing and for mind-altering effects.

The body also produces natural cannabinoids, called endocannabinoids. Cannabinoids act on cannabinoid receptors.

Studies looked at the use of cannabinoids (THC alone and CBD combined with THC) in people with chronic pain. In general, there were improvements in pain measures, but they were not statistically significant.

Cortopassi J. Warfarin dose adjustment required after cannabidiol initiation and titration. Am J Health Syst Pharm. 2020;77(22):1846-1851. View abstract.

Laux LC, Bebin EM, Checketts D, et al. Long-term safety and efficacy of cannabidiol in children and adults with treatment resistant Lennox-Gastaut syndrome or Dravet syndrome: Expanded access program results. Epilepsy Res. 2019;154:13-20. View abstract.

Possibly Effective for

Singh RK, Dillon B, Tatum DA, Van Poppel KC, Bonthius DJ. Drug-Drug Interactions Between Cannabidiol and Lithium. Child Neurol Open. 2020;7:2329048X20947896. View abstract.

Bebee B, Taylor DM, Bourke E, et al. The CANBACK trial: a randomised, controlled clinical trial of oral cannabidiol for people presenting to the emergency department with acute low back pain. Med J Aust. 2021;214(8):370-375. View abstract.

Hess EJ, Moody KA, Geffrey AL, et al. Cannabidiol as a new treatment for drug-resistant epilepsy in tuberous sclerosis complex. Epilepsia. 2016 Oct;57(10):1617-24.View abstract.

In cases of severe allergies, such as anaphylaxis, avoid CBD products altogether.

Certain drugs are more likely to interact with CBD than others — such as antipsychotics, blood thinners, blood pressure medications, and pain medications.

In the bureaucratic language of the WHO — this essentially means there’s a lot of evidence to suggest CBD is safe, and that the side effects are mild and manageable.

4. People Taking Certain Medications (Ask Your Doctor)

Whenever you take medications or supplements, you have to consider how the active compounds interact inside the body. Even if you take them separately, they end up mixing in the digestive tract or bloodstream.

CBD is well-known to offer benefits to specific health conditions. There’s a lot of research on how this compound offers benefits towards diseases such as epilepsy, multiple sclerosis, cancer, arthritis, and more — however, some people may experience a worsening of symptoms after using CBD for their health disorder.

With that said, there are still a few risk factors to consider before using CBD, and about a dozen potential side effects to be aware of.

This is why we encourage people to only order CBD products from companies that publish independent lab analysis for each batch of product they produce.