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benefits of cbd oil for pain

To determine an exact dose of CBD, remember that each drop of oil equals 0.05 mL of fluid. This means that a 30-mL bottle of CBD oil will have roughly 600 drops. If the concentration of the tincture is 1,500 mg/mL, one drop would contain 2.5 mg of CBD (1,500 mg ÷ 600 drops = 2.5 mg).

Since some CBD oils contain trace amounts of THC, you should avoid driving or using heavy machinery when taking CBD oil, particularly when first starting treatment or using a new brand.

Outside of these two disorders, CBD’s effectiveness in treating seizures is uncertain. Even with Epidiolex, it is uncertain whether the anti-seizure effects can be attributed to CBD or some other factor.

How to Calculate CBD Dose

CBD oil comes as full-spectrum oils or in forms that contain CBD isolates. Unlike isolates, which contain CBD only, full-spectrum oils contain a variety of compounds found naturally in the cannabis plant, including proteins, flavonoids, terpenes, and chlorophyll. Alternative practitioners believe these compounds offer more substantial health benefits, although there is no clear evidence of this.

CBD oil can interact with certain medications, including some drugs used to treat epilepsy. CBD inhibits an enzyme called cytochrome P450 (CYP450), which metabolizes certain drugs. By interfering with CYP450, CBD may either increase the toxicity or decrease the effectiveness of these drugs.

Remember, because CBD oils are largely unregulated, there is no guarantee that a product is either safe or effective.

There is currently no known “correct” dose of CBD oil. Depending on individual needs and what is being treated, the daily dose may range between 5 and 25 mg.

Given these benefits, CBD is thought to be helpful in easing the symptoms of the following conditions:

11. Russo, E. Taming THC: potential cannabis synergy and phytocannabinoid-terpenoid entourage effects. Br J Pharmacol. 2011;163(7):1344-1364.

CBD’s Potential Benefits

Overall, the risks of taking CBD are very low, and the rewards can be quite promising. Still, it’s important to remember that more research is needed to understand the full effects of CBD. Your treatment is a personal choice and for many, a personal journey.

6. De Petrocellis L, et al. Effects of cannabinoids and cannabinoid-enriched Cannabis extracts on TRP channels and endocannabinoid metabolic enzymes. Br J Pharmacol. 2011;163(7):1479-1494.

Selecting a CBD product depends on:

Scientists are still trying to determine how CBD oil might alleviate pain. However, there’s some evidence that cannabidiol may affect the body’s endocannabinoid system (a complex system of cell-to-cell communication). Along with contributing to brain functions like memory and mood, the endocannabinoid system influences how we experience pain.

Preclinical animal research suggests that CBD may have moderate pain-relieving effects for neuropathic pain without the cannabinoid-like side effects, however, there is currently a lack of large, well-designed clinical trials (the type of research you want to see to put full stock in a treatment) confirming these effects.

Animal-Based Research

There’s also some concern that taking high doses of cannabidiol may make muscle movement and tremors worse in people with Parkinson’s disease.

As more and more states across the U.S. legalize the use of marijuana, CBD oil has become more widely available. CBD oil is now sold in a range of forms, including capsules, creams, tinctures, and under-the-tongue sprays.

While very few clinical trials have explored the pain-relieving effects of CBD oil, a report published in the Cochrane Database of Systematic Reviews in 2018 examined the use of a variety of cannabis-based medicines and found they might be of some benefit in the treatment of chronic neuropathic pain.